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Regional hyperthermia

In regional hyperthermia, interference patterns in deep seated tumors of the pelvis or lower extremities are generated by an array of phase-controlled antennas radiating in the range of 70 – 150 MHz. These antennas are surrounding the whole circumference of the cross section, i.e. all possible directions are employed to deposit power into the target volume. The higher the number of antennas (and the higher the frequency), the better the potential to control the patterns. In particular, several rings of antennas in direction of the patient axis are useful to enable the flexibility with respect to the anatomical structures for optimization. A frequency of clinical interest is 100 MHz.

Locally advanced and/or recurrent tumors of the pelvis are the major indications for regional hyperthermia, i.e. rectal carcinoma, cervical carcinoma, bladder carcinoma, prostate carcinoma, or soft tissue sarcoma. Some of these indications were validated in prospective studies.